Saccharomyces boulardii
Saccharomyces boulardii is a transient, non-pathogenic yeast used as a probiotic. It survives gastric acidity and is not inactivated by antibiotics, making it highly effective in preventing antibiotic-associated gut flora disruption. It exerts anti-secretory, anti-inflammatory, and trophic effects on the intestinal mucosa.
Dosage by Body Weight
Can be taken with or without food. For sachets, empty the contents into water, milk, juice, or baby formula at room temperature. Do not mix with very hot or frozen liquids, or alcohol, as this can kill the live yeast. For capsules, swallow whole with water. Consult a pediatrician before administering to infants.
- Body Weight
- Below 5 kg
- Dose
- Not routine / 125 mg
- Frequency
- Use only if prescribed by a physician
- Tracking Notes
- Extreme caution is advised in premature infants or severely immunocompromised babies due to the risk of fungemia.
- Body Weight
- 5-7 kg
- Dose
- 250 mg (1 sachet)
- Frequency
- Once daily
- Tracking Notes
- Mix with room temperature breast milk, formula, or water. Ensure child remains well hydrated.
- Body Weight
- 8-10 kg
- Dose
- 250 mg (1 sachet)
- Frequency
- Once daily
- Tracking Notes
- Do not mix with hot food or boiling liquids. Use immediately after mixing.
- Body Weight
- 11-15 kg
- Dose
- 250 mg to 500 mg (1 to 2 sachets/capsules)
- Frequency
- Once or twice daily
- Tracking Notes
- Can split into morning and evening doses. If using capsules, ensure the child can swallow solid dosage forms safely.
- Body Weight
- 16-20 kg
- Dose
- 250 mg to 500 mg
- Frequency
- Once or twice daily
- Tracking Notes
- Maintain adequate oral rehydration therapy alongside probiotic treatment for acute diarrhea.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine / 125 mg | Use only if prescribed by a physician | Extreme caution is advised in premature infants or severely immunocompromised babies due to the risk of fungemia. |
| 5-7 kg | 250 mg (1 sachet) | Once daily | Mix with room temperature breast milk, formula, or water. Ensure child remains well hydrated. |
| 8-10 kg | 250 mg (1 sachet) | Once daily | Do not mix with hot food or boiling liquids. Use immediately after mixing. |
| 11-15 kg | 250 mg to 500 mg (1 to 2 sachets/capsules) | Once or twice daily | Can split into morning and evening doses. If using capsules, ensure the child can swallow solid dosage forms safely. |
| 16-20 kg | 250 mg to 500 mg | Once or twice daily | Maintain adequate oral rehydration therapy alongside probiotic treatment for acute diarrhea. |
Formulation
Purpose
Used as a probiotic to treat and prevent various types of diarrhea, including rotavirus diarrhea in children, antibiotic-associated diarrhea, and traveler's diarrhea. It also helps restore and maintain natural gut flora.
Generic Name
Saccharomyces boulardiiBranded Drug Names
Saccharomyces boulardii is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.